The Laboratory of Ronald G. Crystal, MD, at Weill Cornell Medicine in New York City is recruiting postdoctoral scientists for projects related to gene therapy. The Department conducts a broad range of gene therapy projects from the bench to the clinic including production of GMP vectors for clinical trials. Projects include proof-of-concept models for development of new therapeutic strategies, pre-clinical data generation for regulatory filings, and clinical trial data acquisition and analysis. We are looking for post-doctoral fellows with energy and new ideas who can take advantage of our extensive infrastructure to advance the field of gene therapy. Projects related to GMP vector production are also available. Current pre-clinical and clinical targets include:
- AAV-mediated gene transfer to the CNS for the treatment of Alzheimer’s Disease, lysosomal storage diseases (e.g., Batten disease), and chronic traumatic encephalopathy
- systemic AAV-mediated gene therapy for alpha-1 antitrypsin deficiency, Friedreich’s ataxia, chronic eosinophilia, eosinophilic esophagitis, aldehyde dehydrogenase 2 deficiency, oxidative stress diseases
- adenovirus-based vaccines to treat addiction
In addition, we are actively developing next-generation gene therapy tools and methods of analysis including:
- improved gene expression cassettes
- gene expression control systems
- genome-wide analysis to characterize vector efficacy
- positron-emission tomography to track the fate of gene therapy vectors after delivery
To apply: email your cover letter, names and contact information for three references familiar with your research skills and accomplishments, and your CV to email@example.com; include “Gene Therapy Postdoc” in the subject line. Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.
Candidates must hold a doctoral degree (PhD, MD, or MD/PhD). Successful applicants will be able to carry out independent research with guidance of faculty members, have excellent written and verbal communication skills, demonstrate patience, organizational skills, and collegiality in the laboratory, and practice responsible conduct of research. Candidates are not required to have experience in gene therapy, but should demonstrate productivity through high quality, first author publications in a related field.