The Teruel Lab investigates how cells control cell differentiation by focusing on the critical signaling and transcriptional events and the role of the cell cycle in the differentiation process. We use live-cell imaging approaches to study adipose tissue and its dysregulation in obesity and diabetes. Current projects build on work published in Ahrends et al. (2014) Science, PMID: 24948735; Bahrami-Nejad et al. (2018) Cell Metabolism, PMID: 29617644; and Zhao et al (2020) Cell Reports, PMID: 32553172. You will be joining a new effort that will take a parallel in vitro, organoid, and mouse model strategy to understand a pressing obesity problem how stress-induced flattening of daily glucocorticoid oscillations can initially lead to reversible adipose tissue expansion and later to obesity and insulin resistance. The second project focuses on what is arguably one of the most fundamental problems of all differentiation processes how and why proliferation and differentiation are closely coupled to control tissue size. We are again using the adipose tissue model for which we have developed the methodology to track the full differentiation and proliferation process in live cells in thousands of individual cells. Visit our lab website to find out more: https://meyerteruellabs.org/.
The Teruel Lab is located in newly renovated space. Our lab has multiple state-of the art, ultrafast microscopes setup for long-term, as well as super-resolution, live-cell imaging and photolithography to micropattern matrix to generate in vitro organoid models. We are part of an exceptional academic environment with opportunities for interdisciplinary and collaborative work within Weill-Cornell/Cornell University, Rockefeller University, and Memorial Sloan Kettering Cancer Center. This position offers competitive benefits and access to subsidized Cornell housing in Manhattan and Roosevelt Island.
The ideal candidate should hold a PhD or equivalent. Expertise in mouse physiology or fluorescence microscopy are a plus. Most importantly, the candidate should be interested in learning different technologies as these interdisciplinary projects may involve molecular biology, 3D cell culture, quantitative microscopy, live-cell imaging, or image analysis.
Please send a cover letter and CV, including three references, to Dr. Mary Teruel at firstname.lastname@example.org.