The Neural Connectivity Development in Physiology and Disease Laboratory at the Burke-Cornell Neurological Institute, led by Yutaka Yoshida, Ph.D., is currently seeking a Postdoctoral Fellow with laboratory experience in either molecular biology or neuroscience. The Yoshida laboratory is interested in formation, function, and regeneration of motor circuits controlling locomotor and skilled movements. We especially study descending motor circuits including corticospinal circuits using various techniques such as molecular biology, mouse genetics, trans-synaptic viruses, optogenetic and chemogenetic tools, and spinal cord injury.
Recent representative publications from the Yoshida lab:
- Yoshida Y., Isa T. (2018). Neural and genetic basis of dexterous hand movements. Curr Opin Neurobiol. 52, 25-32.
- Ueno M., Ueno-Nakamura, Y., Li J, Gu Z., Niehaus J., Maezawa M., Crone S.A., Goulding M., Baccei M.L., and Yoshida Y. (2018). Corticospinal circuits from the sensory and motor cortex differentially regulate skilled movements through distinct interneurons. Cell Reports, 23, 1286-1300
- Gu Z., Sarrad N., Ueno M., Liang M., Li J., Enquist L.W., Baccei M.R., Martin J.H., and Yoshida Y. (2017). Skilled movements require non-apoptotic Bax/Bak pathway-mediated corticospinal circuit reorganization. Neuron, 94, 626-641.
- Gu Z., Kalamboglas J., Yoshioka S., Han W., Zhuo L., Imamura Kawasawa Y., Pochareddy S., LiZ., Liu F., Xu X., Wijeratne S., Ueno M., Blatz E., Salomone J., Kumanogoh A., Rasin M.R., Gebelein B., Weirauch M.T., Sestan N., Martin J.H., and Yoshida Y. (2017). Control of species-dependent cortico-motoneuronal connections underlying manual dexterity, Science, 357, 400-404.
- Imai F., Chen X., Weirauch M.T., and Yoshida Y. (2016). Requirement of Dicer in maintenance of monosynaptic sensory-motor circuits in the spinal cord. Cell Reports, 17, 2163-72.
- Ueno M., Ueno-Nakamura Y., Niehaus J., Popovich P.G., and Yoshida Y. (2016). Silencing spinal interneurons inhibits immune suppressive autonomic reflexes caused by spinal cord injury. Nature Neuroscience, 19, 784-787.
Salary for this position ranges from $58,500 - $66,538. Weill Cornell Medicine provides the above salary range in compliance with the New York City law on Salary Transparency in Job Advertisements. The salary range listed is for full‐time employment not including benefits, bonuses, or clinical incentive compensation where applicable. The above salary range for New York City based roles represents WCM’s good faith and reasonable estimate of possible compensation at the time of posting. Weill Cornell Medicine is an Equal Employment Opportunity Employer and provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.
Contact
- Burke Neurological Institute