Postdoctoral fellow position to study the role of the ubiquitin-proteasome system (UPS) in antitumor immunity
The Marzio lab at Weill Cornell Medicine has an available position to hire a highly motivated, creative, and enthusiastic postdoctoral fellow. Located in the Department of Pathology and Laboratory Medicine at Weill Cornell Medicine, the Marzio Lab investigates how deregulation of the ubiquitin-proteasome system (UPS) promotes cancer progression, with a particular emphasis on the DNA damage response (DDR) and antitumor immunity. To address this question, we use multidisciplinary approaches including biochemistry, cell signaling, mouse models of tumorigenesis, and pharmacotherapy.
Applicants should have recently completed their graduate degree (PhD or MD/PhD) with a background in biochemistry, and/or molecular and cellular biology. The successful candidate will lead projects to elucidate the role of E3 ubiquitin ligases (E3s) in antitumor immunity and dissect the biochemical and molecular mechanisms that drive tumorigenesis via deregulation of the E3s activity. The primary responsibility will be to design and perform benchwork independently to build confidence-in-rationale for novel targets in immune-oncology area and publish results in international meeting and peer-reviewed journals. The postdoc will utilize a multidisciplinary approach that will leverage a broad spectrum of experimental systems and levels of resolution (atomic, molecular, network, cellular, tissue, and organismal). In addition, the successful candidate will be encouraged to develop their own research ideas along the lines of the research interest of the lab. You will join a vibrant and fun lab environment and be part of a multidisciplinary team in a stimulating academic setting, with plenty of resources for intellectual and career development, as well as strong mentoring.
Key responsibilities of this role include, but are not limited to:
• Independently design, develop and test biological hypotheses.
• Interrogate novel cellular and molecular biology.
• Work independently to execute hands-on experiments and analyze data.
• Publish research findings in top-tier publications.
• Effectively present data in internal and external meetings.
• Drive multiple exploratory projects, and work collaboratively with research associate and graduate students.
Education and Qualifications
• Recent Ph.D. in molecular and cell biology, biochemistry, oncology, or a related field.
• Strong track record demonstrated in the context of driving target discovery and validation projects and
reflected in a strong record of achievement in peer-reviewed publications (i.e., at least one first author
• Strong hands-on expertise and solid skills in molecular/cell biology and biochemistry.
• Ability to work in a team environment, excellent data handling and recording skills as well as oral and written
• Ability of trouble shooting and data analysis.
• Prior mouse handling experience and flow cytometry knowledge.
If you are a dynamic team member, curious thinker, and careful experimentalist please consider joining our team and email Dr. Antonio Marzio (firstname.lastname@example.org). Please also visit:
Salary Range is: $58,500 - $65,320
Weill Cornell Medicine provides the above salary range in compliance with the New York City law on Salary Transparency in Job Advertisements. The salary range listed is for full‐time employment not including bonuses, clinical incentive compensation, or benefits. Actual salaries depend on a variety of factors including but not limited to internal equity, specialty, training, and hospital/community needs.
The above salary range for New York City based roles represents WCM’s good faith and reasonable estimate of possible compensation at the time of posting.