The laboratory of Dr. David Rickman at Weill Cornell Medicine (WCM) in New York City is seeking a highly motivated postdoctoral fellow with experience in transcription factor biology or epigenomic modifiers. The fellow will work on a project using a translational approach and builds on previous work from the Rickman lab (Cancer Discovery, 2011, Cancer Cell, 2016 and J. Clin. Investigation, 2019) characterizing the role of transcription factors, interacting cofactors and epigenetic modifiers in driving castrate resistant prostate cancer, lineage plasticity and the development of neuroendocrine prostate cancer (NEPC). There is ample funding (NIH-R01, NIH-Prostate Cancer SPORE, DOD-IMPACT awards) for this project.
He/she will lead a pharma-funded project that focuses on the development of novel therapeutic strategies for NEPC. This project will involve interactions with physicians, physician/scientists at WCM, the Dana Farber Cancer Center (Boston) and pharmaceutical companies. This project will leverage a new inducible genetically engineered mouse (GEM) model that will allow for temporal control of N-Myc expression and lineage tracing. Studies will be performed in combination with available in vitro, ex vivo and in vivo models (e.g. cell lines, human and mouse prostate cancer organoids, patient derived xenografts and GEM models).
Highly motivated applicants must possess a PhD or equivalent and research experience with in vitro and in vivo drug dosing, tracking tumor volume, and in vivo imaging. Experience with genome-wide analyses (RNAseq, ChIPseq, ATACseq) is a plus. Long-term goals for this fellow will be to develop as a prostate cancer translational scientist.
Other qualifications and requirements include a strong record of scientific productivity with publications as first author in internationally renowned journals, critical thinking and organizational skills with supervisory experience. The individual should have experience with working in teams, as well as an ability to work independently.
Salary and benefits commensurate with experience and NIH guidelines Applicants who are interested in this position should e-mail:
1) Statement of research interests and career goals
2) Curriculum Vitae including bibliography
3) Names and contact information for two or three references
David S. Rickman, Ph.D.
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College
Salary Range is: $58,500 - $65,320
Weill Cornell Medicine provides the above salary range in compliance with the New York City law on Salary Transparency in Job Advertisements. The salary range listed is for full‐time employment not including bonuses, clinical incentive compensation, or benefits. Actual salaries depend on a variety of factors including but not limited to internal equity, specialty, training, and hospital/community needs.
The above salary range for New York City based roles represents WCM’s good faith and reasonable estimate of possible compensation at the time of posting.